BiteFirst provides IT services to charities/non-profit, small and medium size organisations (e.g. medical research departments) in London, Norfolk and online with a primary focus on bespoke development of secure database driven WEB (Rails, Python, PostgreSQL) based applications to support back office business functions such as large volume simulations, billing, recruitment, reporting and database analysis. Cloud based solutions that are secure, fast and accessible from PCs, Tablets or Smartphones.
If you have a current or potential business need for a WEB site or a more complex solution, advice is free, just make contact via email.
Have infrastructure and skills to prepare (Biopython), process and manage (PostgreSQL) the results for large scale NetMHCpan gene sequence simulations (e.g., 1000s of sequences, multiple HLA, results in billions in databases). Pro bono support work undertaken.
SARS-CoV-2 Paper "Sampling SARS-CoV-2 proteomes for predicted CD8 T-cell epitopes as a tool for understanding immunogenic breadth and rationale vaccine design" : https://www.frontiersin.org/articles/10.3389/fbinf.2021.622992/full
Utilizing Computational Machine Learning Tools to Understand Immunogenic Breadth in the Context of a CD8 T-Cell Mediated HIV Response." (see www.biorxiv.org/content/biorxiv/early/2020/08/17/2020.08.15.250589.full.pdf).
Delivered an Immunogenic Breadth Prediction Tool (IBPT) tool for IAVI and Imperial that evaluates virus proteome diversity (SARS_CoV_2 and HIV to date). Web (Rails) user interface to a PostgreSQL database on Unix server running NetMHCpan simulations and bespoke Python analysis programs. Large quantities of NetMHCpan simulations were run on multiple low cost virtual Unix cloud servers.
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